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RAD23B Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527902

Catalog No. PIPA527902


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Description

Description

PA5-27902 targets RAD23B in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-27902 immunogen is recombit fragment corresponding to a region within amino acids 1 and 338 of Human RAD23B. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Specifications

Specifications

RAD23B
Polyclonal
Unconjugated
RAD23B
Liquid
RAD23B
Recombit fragment corresponding to a region within amino acids 1 and 338 of Human RAD23B
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.69 mg/mL
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
P54727
HHR23B, HR23B, P58, RAD23, yeast homolog of, B, UV excision repair protein RAD23 homolog B, XP-C repair complementing complex 58 kDa, XP-C repair complementing protein, XP-C repair-complementing complex 58 kDa protein
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
5887
Documents
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