RANBP1 Goat anti-Human, Polyclonal, Invitrogen
Goat Polyclonal Antibody
Manufacturer: Invitrogen PA19093
DescriptionRan/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
|Synthetic peptide corresponding to the C terminus amino acids LSVKEETKEDAEEKQ.|
|Antigen affinity chromatography|
|Immunohistochemistry, Western Blot|
|TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3|
|RANBP1; RAN binding protein 1|
|-20° C, Avoid Freeze/Thaw Cycles|
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