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RANBP1 Goat anti-Human, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA19093

Catalog No. 01-674-675


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Description

Description

Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
Specifications

Specifications

RANBP1
Polyclonal
Unconjugated
RANBP1
Liquid
RANBP1
Synthetic peptide corresponding to the C terminus amino acids LSVKEETKEDAEEKQ.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry, Western Blot
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
P43487
RANBP1; RAN binding protein 1
Goat
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
5902
Documents
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