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RANK Goat anti-Human, Mouse, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA124722

Catalog No. PIPA124722


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Description

Description

PA1-24722 detects RANK from human and mouse samples. PA1-24722 has been successfully used in Western blot procedures. The PA1-24722 immunogen is purified, recombit human RANK extracelluar domain, expressed in mouse NSO cells. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Studies of the mouse counterpart suggest that this receptor directly mediates the osteoprotegerin ligand (OPGL)-induced osteoclastogenesis in osteoclast precursor cells.
Specifications

Specifications

RANK
Polyclonal
Unconjugated
TNFRSF11A
Liquid
TNFRSF11A
Purified, recombit human RANK extracelluar domain, expressed in mouse NSO cells.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
ELISA, Western Blot
0.1 mg/mL
PBS with no preservative
Q9Y6Q6, O35305
FEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER, TNFRSF11A
Goat
IgG
25 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
21934, 8792
Documents
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