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CCL5 (RANTES) Mouse anti-Human, Clone: 21418, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523709

Catalog No. PIMA523709


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Description

Description

When used in combination with the biotinylated anti-human CCL5/RANTES detection antibody in sandwich ELISAs, no significant cross-reactivity or interference is observed with recombit human (rh) ANG, rhCNTF, rh beta -ECGF, rhEGF, mouse (m) EGF, rhEpo, bovine (b) FGF acidic, rhFGF acidic, bFGF basic, rhFGF basic, rhFGF-4, rhG-CSF, rhGM-CSF, recombit mouse (rm) GM-CSF, rhGRO alpha, rhIFN-gamma, rhIGF-I, rhIGF-II, rhIL-1 alpha, rmIL-1 alpha, rhIL-1 beta, rmIL-1 beta, rhIL-1ra, recombit rat (rr) IL-1ra, rhIL-2, rhIL-3, rmIL-3, rmIL-4, rhIL-5, rmIL-5, rhIL-6, rmIL-6, rhIL-7, rmIL-7, rhIL-8, rhIL-9, rmIL-9, rhIL-10, rhIL-11, rhLIF, rhMCP-1, rhM-CSF, rhMIP-1 alpha, rmMIP-1 alpha, rhMIP-1 beta, rmMIP-1 beta, rhOSM, human (h) PDGF, pPDGF, rhPDGF-AA, rhPDGF-AB, rhPDGF-BB, rhSCF, rmSCF, rhSLPI, rhTGF-alpha, pTGF-beta 1, hTGF-beta 1, rhTGF-beta 1, pTGF-beta 2, rhTGF-beta 2, recombit canine TGF-beta 3, rhTGF-beta 3, recombit amphibian TGF-beta 5, rhTNF-alpha, rmTNF-alpha, or rmTNF-beta. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.
Specifications

Specifications

CCL5 (RANTES)
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P13501
C-C motif chemokine 5, SIS-delta, T-cell specific protein p288, T-cell-specific protein RANTES, beta-chemokine RANTES, eoCP, eosinophil chemotactic cytokine, small inducible cytokine A5, t cell-specific protein P228, D17S136E, MGC17164, SCYA5, SISd, TCP228
Mouse
IgG1
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
6352
ELISA, Neutralization, Western Blot
21418
Unconjugated
CCL5
Lyophilized
CCL5
E. coli-derived recombit human CCL5/RANTES
Protein A/G
RUO
Antibody
Monoclonal
Human
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