CCL5 (RANTES) Rat anti-Mouse, Clone: 53433, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA523750
This antibody detects Recombinant mouse (rm)CCL5 direct ELISAs. In sandwich ELISAs, approximately 5% cross-reactivity with rhCCL5 and less than 0.2% cross-reactivity with rhTECK and rhVIC was observed. Reconstitute at 0.5 mg/mL in sterile PBS.This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.
|PBS with 5% trehalose and No Preservative|
|C-C motif chemokine 5, SIS-delta, T-cell specific protein p288, T-cell-specific protein RANTES, beta-chemokine RANTES, eoCP, eosinophil chemotactic cytokine, small inducible cytokine A5, t cell-specific protein P228, D17S136E, MGC17164, SCYA5, SISd, TCP228|
|-20° C, Avoid Freeze/Thaw Cycles|
|E. coli-derived recombit mouse CCL5/RANTES Ser24-Ser91|
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