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CCL5 (RANTES) Rat anti-Mouse, Clone: 53433, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA523750

Catalog No. PIMA523750


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Description

Description

This antibody detects Recombinant mouse (rm)CCL5 direct ELISAs. In sandwich ELISAs, approximately 5% cross-reactivity with rhCCL5 and less than 0.2% cross-reactivity with rhTECK and rhVIC was observed. Reconstitute at 0.5 mg/mL in sterile PBS.

This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.
Specifications

Specifications

CCL5 (RANTES)
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P30882
C-C motif chemokine 5, SIS-delta, T-cell specific protein p288, T-cell-specific protein RANTES, beta-chemokine RANTES, eoCP, eosinophil chemotactic cytokine, small inducible cytokine A5, t cell-specific protein P228, D17S136E, MGC17164, SCYA5, SISd, TCP228
Rat
IgG1
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
20304
ELISA
53433
Unconjugated
Ccl5
Lyophilized
CCL5
E. coli-derived recombit mouse CCL5/RANTES Ser24-Ser91
Protein A/G
RUO
Antibody
Monoclonal
Mouse
Documents
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