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CD1d Mouse anti-Rat, Unlabeled, Clone: WTH2 (also known as WTH-2), BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 564633

Catalog No. BDB564633


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Description

Description

The WTH2 monoclonal antibody specifically binds to rat CD1d and crossreacts with mouse CD1d. CD1d is a type I transmembrane glycoprotein that is noncovalently associated with β2-microglobulin. CD1d is expressed on various cell types including subsets of thymocytes, T cells, B cells, monocytes, macrophages, dendritic cells, endothelial cells and epithelial cells. Although structurally similar to MHC Class I antigens, CD1d molecules are rather non-polymorphic and serve to present non-peptide antigens such as endogenous or microbial glycolipids to T lymphocytes (NKT cells). The WTH1 monoclonal antibody reportedly binds to a non-overlapping epitope on rat CD1d and also crossreacts with mouse CD1d when compared with WTH2. Both WTH1 and WTH2 reportedly interfere with antigen recognition by CD1d-restricted T cells.

Specifications

Specifications

CD1d
WTH2 (also known as WTH-2)
Unconjugated
Aqueous buffered solution containing ≤0.09% sodium azide.
Murine
IgG2a, κ
0.1mg
Store undiluted at 4°C
Monoclonal
Flow Cytometry
0.5mg/mL
Cd1d; Antigen-presenting glycoprotein CD1d
Affinity Purified
Rat CD1d Transfected Cell Line
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
RUO
Primary
Murine, Rat
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