Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

anti-LBP, Clone: M300-19, Novus Biologicals™

Rat Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP142426

Catalog No. NBP142426


Add to cart

Description

Description

LBP Monoclonal antibody specifically detects LBP in Mouse samples. It is validated for Western Blot.
Specifications

Specifications

LBP
M300-19
Western Blot 1:100-1:2000
Purified
LBP
The antibody reacts with the LBP antigen.
Protein A or G purified
RUO
Primary
3929
Mouse
Western Blot
Unconjugated
PBS containing 0.1% BSA with 0.02% Sodium Azide
lipopolysaccharide binding protein, lipopolysaccharide-binding protein, LPS-binding protein, MGC22233
Rat
IgG2a
0.05 mg
Store at 4C. Do not freeze.
Monoclonal
The monoclonal antibody M330-19 reacts highly specific with mouse natural and recombinant LBP. The antibody is a type I antibody blocking the LPS binding to LBP. LPS binding protein (LBP) is an approximately 60 kDa acute phase protein that is produced by hepatocytes. This protein strongly binds to LPS and has been shown to play an important role in the handling of LPS by the host. A number of functions of LBP have been reported. First, LBP transfers LPS to the LPS receptor CD14 on mononuclear phagocytes, leading to an 100-1,000-fold increased sensitivity of the cells to LPS. Furthermore, LBP can enhance the response of CD14 negative cells by acceleration of LPS binding to soluble CD14, a complex that stimulates these cells. Next, LBP transfers LPS into High Density Lipoprotein (HDL), which effectively neutralizes its biological potency. LBP was demonstrated to protect mice from septic shock caused by LPS or gram negative bacteria.
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only