CtIP Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520963
A suggested positive control is mouse spleen tissue lysate. PA5-20963 can be used with blocking peptide PEP-1077.RBBP8, also known as CtBP (carboxy-terminal binding protein) interacting protein (CTIP), was characterized for its role in transcription as a cofactor for the transcriptional repressor CtBP, and also as a binding partner for other proteins including the cell cycle regulators retinoblastoma protein (Rb) and breast cancer 1 (BRCA1). It is ubiquitously expressed and localizes to the nucleus. RBBP8 is thought to modulate the functions in cell proliferation, transcriptional regulation and DNA repair. RBBP8 also plays a central role in the cell cycle checkpoint response to DNA double-stranded breaks (DSBs), with new evidence demonstrating that it controls the choice of DSB repair pathway.
|A 14 amino acid peptide near the center of human RBBP8.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|Q99708, Q80YR6, B1WC58|
|CTIP, RIM, SAE2; CTBP-interacting protein; DNA endonuclease RBBP8; RBBP-8; sporulation in the absence of SPO11 protein 2 homolog|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|225182, 291787, 5932|
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