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CtIP Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520963

Catalog No. PIPA520963


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Description

Description

A suggested positive control is mouse spleen tissue lysate. PA5-20963 can be used with blocking peptide PEP-1077.

RBBP8, also known as CtBP (carboxy-terminal binding protein) interacting protein (CTIP), was characterized for its role in transcription as a cofactor for the transcriptional repressor CtBP, and also as a binding partner for other proteins including the cell cycle regulators retinoblastoma protein (Rb) and breast cancer 1 (BRCA1). It is ubiquitously expressed and localizes to the nucleus. RBBP8 is thought to modulate the functions in cell proliferation, transcriptional regulation and DNA repair. RBBP8 also plays a central role in the cell cycle checkpoint response to DNA double-stranded breaks (DSBs), with new evidence demonstrating that it controls the choice of DSB repair pathway.
Specifications

Specifications

CtIP
Polyclonal
Unconjugated
RBBP8
Liquid
RBBP8
A 14 amino acid peptide near the center of human RBBP8.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q99708, Q80YR6, B1WC58
CTIP, RIM, SAE2; CTBP-interacting protein; DNA endonuclease RBBP8; RBBP-8; sporulation in the absence of SPO11 protein 2 homolog
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
225182, 291787, 5932
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