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ESRP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521109

Catalog No. PIPA521109


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Description

Description

A suggested positive control is rat colon lysate. PA5-21109 can be used with blocking peptide PEP-1223.

RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5 ft. UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.
Specifications

Specifications

ESRP1
Polyclonal
Unconjugated
ESRP1
Liquid
ESRP1
An 18 amino acid peptide near the amino terminus of human RBM35A.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q6NXG1, Q3US41, B2RYD2
RBM35A, RMB35A; RNA binding motif protein 35A; RNA-binding motif protein 35A; RNA-binding protein 35A
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
207920, 500409, 54845
Documents
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