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RCAN1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523027

Catalog No. PIPA523027


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Description

Description

In Western blot, a band is seen at ~38 kDa, representing isoform RCAN1-1L.

The RCAN1 protein interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. This antibody is specific for Isoform RCAN1-1L, which is overexpressed in Alzheimer ft.s Disease (Harris, C.D. et al) and is downregulated in Huntington ft.s Disease (Ermak, G. et al).
Specifications

Specifications

RCAN1
Polyclonal
Unconjugated
RCAN1
Liquid
RCAN1
Synthetic peptide made to an internal portion of the human protein (within residues 40-90).
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 30% glycerol and 0.1% sodium azide
P53805, Q9JHG6
ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1, Down syndrome candidate region 1, Down syndrome critical region gene 1, calcipressin-1, calcium and oxidant-inducible mRNA, down syndrome critical region protein 1, modulatory calcineurin-interacting protein 1, myocyte-enriched calcineurin-interacting protein 1, near DSCR proline-rich protein
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
1827, 54720
Documents
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