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RCC1 Mouse, Unlabeled, Clone: 9, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610377

Catalog No. BDB610377


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Description

Description

RCC1 (Regulator of Chromosome Condensation) is a chromatin-associated protein implicated in a number of cellular processes such as nuclei formation, initiation/termination of transcription, pre-mRNA splicing/3 ft.-end formation, mRNA export and DNA replication. Normally, RCC1 appears to play a structural role with chromatin. This nuclear protein can function as a guanine nucleotide exchange factor for the Ras-like GTPase, Ran/TC4. Loss of RCC1 expression is related to a structural transition of the chromosome and correlates with the inability of the cells to detect unreplicated DNA. RCC1 appears to be necessary for nucleocytoplasmic transport of precursors of spliceosomal small nuclear RNAs (snRNAs), intranuclear transport of U3 snRNA and processing of ribosomal RNAs, but not for export of transfer RNAs.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

Specifications

RCC1
9
Unconjugated
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Murine
IgG1
RUO
Store undiluted at -20°C.
Monoclonal
Western Blot
250μg/mL
Regulator of Chromosome Condensation-1
Affinity Purified
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
50μg
Cell Biology
Primary
Canine, Human
Documents
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