RCC1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528063
PA5-28063 targets RCC1 in IF, IHC (P), and WB applications and shows reactivity with Human and Mouse samples. The PA5-28063 immunogen is recombit fragment corresponding to a region within amino acids 2 and 421 of Human RCC1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
|Recombit fragment corresponding to a region within amino acids 2 and 421 of Human RCC1|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|CHC1, RCC1-I, SNHG3-RCC1, SNHG3-RCC1 readthrough transcript, cell cycle regulatory protein, guanine nucleotide-releasing protein, regulator of chromosome condensation|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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