RELM alpha Rat anti-Mouse, Clone: 226033, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA523898
In direct ELISAs and Western blots, this antibody does not cross-react with recombit mouse (rm) RELM beta or rmResistin. Reconstitute at 0.5 mg/mL in sterile PBS.A family of resistin-like molecules (RELMs) has been identified in rodents and humans. Resistin is a hormone produced by fat cells. RELM alpha is a secreted protein that has a restricted tissue distribution with highest levels in adipose tissue. Another family member, RELM beta, is a secreted protein expressed only in the gastrointestinal tract, particularly the colon, in both mouse and human. RELM beta gene expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation. Resistin and the RELMs share a cysteine composition and other signature features. Thus, the RELMs together with resistin comprise a class of tissue-specific signaling molecules.
|PBS with 5% trehalose and No Preservative|
|FIZZ1, FIZZ2, HXCP2, RELM-beta, RELMb, RELMbeta, XCP2|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|E. coli-derived recombit mouse RELM alpha Asp24-Ser111|
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