Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

RARB Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA1811

Catalog No. PA1811


Add to cart

Description

Description

PA1-811 detects retinoic acid receptor (RAR) beta from human and mouse tissues. This antibody shows slight cross-reactivity to RAR alpha but does not detect RAR gamma. PA1-811 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~52 kDa protein representing RAR beta from SH-SY5Y (human neuroblastoma) cell extract. The PA1-811 immunogen is a synthetic peptide corresponding to residues P(429) S V S P S S V E N S G V S Q S P L L Q(448) of mouse RAR beta. This immunizing peptide (Cat. No. PEP-005) is available for use in neutralization and control experiments.

Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma. RAR beta is also known as HAP. The corresponding gene for the retinoic acid receptor beta is NR1B2.
Specifications

Specifications

RARB
Polyclonal
whole serum diluted in PBS with 0.05% sodium azide
P10826, P22605
RAR Beta, RAR-Epsilon, HAP, RAR-Beta2, RAR-Beta4, NR1B2
Rabbit
IgG
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
RARB
Liquid
RARB
Synthetic peptide corresponding to residues P(429) S V S P S S V E N S G V S Q S P L L Q(448) of mouse RAR beta.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
218772, 5915
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit