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ROR gamma Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523148

Catalog No. PIPA523148


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Description

Description

ROR-gamma is a 560 amino acid novel DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. The specific functions of this protein are not known. However, reports suggest that this protein is a ligand activated transcription factor and may be essential for lymphoid organogenesis (lymph nodes and Peyer ft.s patches) and may play an important regulatory role in controlling apoptosis during thymopoiesis. ROR-gamma inhibits the expression of Fas ligand and IL2 and directs the differentiation program of proinflammatory IL-17+ T helper cells. ROR-gamma shares 50 to 51% sequence identity with RORA and RORB and is 88% identical to mouse ROR-gamma. It is highly expressed in skeletal muscle and at lower levels in various other tissues.
Specifications

Specifications

ROR gamma
Polyclonal
Unconjugated
RORC
Liquid
RORC
Synthetic peptide (2 DRAPQRQHRASRELLAAKKTHTSQIE 27) of Retinoid-Related Orphan Receptor Gamma (RORg/NR1F3) protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P51449, P51450
RP11-98D18.11-001, NR1F3, RORG, RZR-GAMMA, RZRG, TOR, RAR-related orphan nuclear receptor variant 2, nuclear receptor ROR-gamma, nuclear receptor RZR-gamma, nuclear receptor subfamily 1 group F member 3, retinoic acid-binding receptor gamma, retinoid-related orphan receptor gamma
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
19885, 6097
Documents
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