RXRG Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA138583
Retinoids are metabolites of vitamin A (retinal) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation. Two families of retinoid receptors have been identified.Retinoic acid receptors (RARs) include RARalpha, RARBeta and RARgamma, each of which has a high affinity for all-trans retinoic acids and belongs to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. Members of the retinoid X receptor (RXR) family, RXRalpha, RXRBeta and RXRgamma, are activated by 9-cis-retinoic acid, a stereo- and photoisomer of all-trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used.Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is breast or prostate carcinoma.
|Synthetic peptide derived from N-terminus of mouse RXR gamma|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA and 0.1% sodium azide; pH 7.6|
|Retinoid X recptor gamma|
|-20° C, Avoid Freeze/Thaw Cycles|
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