replication factor C (activator 1) 4, 37kDa, Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a full-length human RFC4 protein.
Manufacturer: Abnova Corporation H00005984B01
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36kDa. This gene encodes the 37kDa subunit. This subunit forms a core complex with the 36 and 40kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeqSequence: MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLSQNC
|replication factor C (activator 1) 4, 37kDa|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Mouse polyclonal antibody raised against a full-length human RFC4 protein.|
|RFC4 (NP_002907, 1 a.a. ~ 363 a.a) full-length human protein.|
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