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RFC5, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA126571

Catalog No. PIPA126571

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

PA1-26571 detects RFC5 from human samples. PA1-26571 will not react with mouse or rat.PA1-26571 has been successfully used in Western blot procedures where a band of 36kDa is predicted to be detected. HeLa cell nucleaer extract is recommended as a positive control fo PA1-26571.The PA1-26571 immunogen is a synthetic peptide corresponding to a portion of human Replication Factor C 5 36kDa subunit encoded within exon 1.
Specifications

Specifications

RFC5
Polyclonal
Unconjugated
RFC5
Purified
RFC5
Synthetic peptide corresponding to a portion of human Replication Factor C 5 36 kDa subunit encoded within exon 1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Western Blot
1mg/mL
tris phosphate, tris citrate with 0.1% sodium azide; pH 7-8
P40937
MGC1155, RFC36
Goat
IgG
50μL
Store at 4°C
Primary
5985
Documents
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