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RFXANK, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA122855

Catalog No. PIPA122855

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

MHC class II deficiency is an autosomal recessive immunodeficiency syndrome resulting from defects in transacting factors essential for transcription of MHC class II genes. There are 4 genetic complementation groups (A, B, C, and D), reflecting the existence of 4 MHC class II regulators. Group B is characterized by a defect in RFX binding, and although it accounts for the majority of patients, the factor defective in group B remained unknown until Masternak et al. (1998) isolated RFX by a novel single-step DNA-affinity purification approach and identified RFXANK, the gene encoding the third subunit of RFX. The gene was symbolized RFXANK because the protein contains 3 ankyrin repeats.

PA1-22855 detects RFXANK in Human samples.PA1-22855 has been successfully used in Immunoprecipitation and Western Blot procedures.PA1-22855 immunogen corresponds to Syn. Pep. of last 100 aa of the Hu RFXANK (GenBank PID 4506499) conjugated to KLH.
Specifications

Specifications

RFXANK
Polyclonal
Unconjugated
RFXANK
Purified
RFXANK
Syn. Pep. of last 100 aa of the Hu RFXANK (GenBank PID 4506499) conjugated to KLH
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunoprecipitation, Western Blot
1mg/mL
tris citrate, tris phosphate with 0.1% sodium azide; pH 7-8
O14593
ANKRA1, BLS, F14150_1, MGC138628, RFX-B
Rabbit
IgG
50μg
Store at 4°C
Primary
8625
Documents
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