RFXAP Mouse anti-Human, Clone: 1B5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA519814
Peptide Sequence: SDQALNCGGT ASTGSAGNVK LEESADNILS IVKQRTGSFG DRPARPTLLE QVLNQKRLSL LRSPEVMajor histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene.
|PBS with no preservative; pH 7.4|
|RFX-AP, Regulatory factor X-associated protein, RFX-associated protein, RFX DNA-binding complex 36 kDa subunit|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|RFXAP (NP_000529, 179 a.a. ∽ 244 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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