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RFXAP Mouse anti-Human, Clone: 1B5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA519814

Catalog No. PIMA519814


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Description

Description

Peptide Sequence: SDQALNCGGT ASTGSAGNVK LEESADNILS IVKQRTGSFG DRPARPTLLE QVLNQKRLSL LRSPEV

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene.
Specifications

Specifications

RFXAP
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.4
O00287
RFX-AP, Regulatory factor X-associated protein, RFX-associated protein, RFX DNA-binding complex 36 kDa subunit
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
5994
ELISA, Western Blot
1B5
Unconjugated
RFXAP
Liquid
RFXAP
RFXAP (NP_000529, 179 a.a. ∽ 244 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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