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RGS13 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523109

Catalog No. PIPA523109


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Description

Description

RGS13 is the smallest member of the mammalian gene family, RGS (regulators of G protein-signaling) which are structural and functional homologues of yeast SST2 and C. elegans egl-10 proteins. RGS proteins attenuate G protein-mediated pathways by acting as GTPase-activating proteins (GAPs) for Ga subunits. RGS13 has been found most abundantly in human tonsil, thymus, lung, lymph node, and spleen. RGS13 regulate Gai, Gaq, and Gas coupled signaling cascades. It is a GTPase-activating protein for Gai and Gao. The protein blocks MAPK activity induced by Gai- or Gaq-coupled receptors. The protein also attenuates GTPase-deficient Gaq (GaqQL) mediated cAMP response element activation. The gene encoding for human RGS13 is localized on chromosome 1q31.2.
Specifications

Specifications

RGS13
Polyclonal
whole serum with 50% glycerol and 0.025% sodium azide
O14921
RP11-92K2.1, regulator of G-protein signalling 13
Rabbit
IgG
RUO
Antibody
Polyclonal
Human
Western Blot
Unconjugated
RGS13
Liquid
RGS13
Synthetic peptide (AA 67-86, CETYKKIASRWSRISRAKKL) of RGS13 protein.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
6003
Documents
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