RGS4, Polyclonal, Invitrogen
Chicken Polyclonal Antibody
Manufacturer: Invitrogen PA129479
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene.PA1-29479 detects RGS4 from mouse, human, rat samples.PA1-29479 has been successfully used in Western blot applications.The PA1-29479 immunogen is: Amino acids 127-205 of RGS4.Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
|PBS with no preservative|
|P49798, O08899, P49799|
|RP11-430G6.1, DKFZp761F1924, MGC2124, MGC60244, RGP4, SCZD9|
|Store at 4°C short term. For long term storage, Store at -20°C, avoiding freeze/thaw cycles.|
|Amino acids 127-205 of RGS4.|
|Antigen affinity chromatography|
|Human, Murine, Rat|
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