D4-GDI Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527873
PA5-27873 targets Rho GDI2 in WB applications and shows reactivity with Human samples. The PA5-27873 immunogen is recombit fragment corresponding to a region within amino acids 1 and 201 of Human Rho GDI2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).
|Recombit fragment corresponding to a region within amino acids 1 and 201 of Human Rho GDI2|
|Antigen affinity chromatography|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2, Rho GDI 2, rho GDP-dissociation inhibitor 2, rho-GDI beta|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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