anti-RIT1 Polyclonal, Thermo Scientific™

RIT1 Polyclonal antibody PA1-12571 from Thermo Scientific™ specifically detects RIT1 in Human samples, and it is validated for Western Blot

Manufacturer: Invitrogen PA112571

 View more versions of this product

Catalog No. 01-674-798

  Check Availability
Add to Cart

    Specifications

    Antigen RIT1
    Applications Western Blotting
    Conjugate Unlabeled
    Cross Reactivity Human
    Format Purified
    Formulation 100μg purified antibody in PBS and 0.08% sodium azide
    Gene Accession No. Q92963
    Gene Alias MGC125864, MGC125865, RIBB, RIT, ROC1
    Gene Symbols RIT1
    Host Species Rabbit
    Immunogen His-tagged recombinant human Rit protein.
    Isotype IgG
    Quantity 100μg
    Species Reactivity Human
    Storage Requirements Avoid Freeze/Thaw Cycles
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Gene ID (Entrez) 6016

    RIT1 Polyclonal antibody PA1-12571 from Thermo Scientific™ specifically detects RIT1 in Human samples, and it is validated for Western Blot

    Rit and its neuron-specific homologue, Rin, define a recently discovered subfamily of Ras-related GTPases. Rit and Rin are membrane-associated in spite of the fact that they lack a CAAX box or similar C-terminal lipidation motif. Rit and Rin display 64% amino acid sequence identity and share a unique nine amino acid effector domain (DPTIEDAYK) that is 100% conserved between the murine and human proteins. Although the effector domain sequences of Rit and Rin are very similar to that of Ras, Rit and Rin have been shown to interact with the known Ras-binding proteins RalGDS, Rlf and AF-6, but not the Raf kinases, RIN1 or the p110 subunit of PI3 kinase. For this reason, it has been suggested that Rit and Rin may play important roles in the regulation of signaling pathways distinct from those controlled by Ras.
    Host Species: Rabbit
    Cross Reactivity: Human
    Isotype: IgG
    Immunogen: His-tagged recombinant human Rit protein.
    Formulation: 100µg purified antibody in PBS and 0.08% sodium azide
    Synonyms: MGC125864, MGC125865, RIBB, RIT, ROC1
    Uniprot Accession: Q92963
    Entrez GeneID: 6016
    Gene Symbol: RIT1
    This product detects RIT1 in Human samples. This product has been successfully used in Western Blot procedures. The immunogen is His-tagged recombinant human Rit protein..

  • Description & Specifications

Related Products


Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit