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RKHD2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520622

Catalog No. PIPA520622


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Description

Description

A suggested positive control is rat heart tissue lysate. PA5-20622 can be used with blocking peptide PEP-0742.

Rkhd2, also known as MEX3C is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd2, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. It has been suggested that genetic variations in Rkhd2 may be associated with susceptibility to essential hypertension type 8. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
Specifications

Specifications

Rkhd2
Polyclonal
Unconjugated
MEX3C
Liquid
MEX3C
A 15 amino acid peptide from near the carboxy terminus of human RKHD2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q5U5Q3, Q05A36
BM-013, MEX-3C, RKHD2, RNF194; RING finger and KH domain-containing protein 2; RING finger protein 194; RNA-binding protein MEX3C; ring finger and KH domain containing 2
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
240396, 307271, 51320
Documents
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