RNF14 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA529456
PA5-29456 targets RNF14 in WB applications and shows reactivity with Human samples. The PA5-29456 immunogen is recombit fragment corresponding to a region within amino acids 1 and 260 of Human RNF14. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A domit negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
|Recombit fragment corresponding to a region within amino acids 1 and 260 of Human RNF14|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7|
|ARA54, HFB30, TRIAD2, E3 ubiquitin-protein ligase RNF14, androgen receptor associated protein 54, androgen receptor-associated protein 54|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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