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C18orf23 Mouse anti-Human, Rat, Clone: 3A1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523079

Catalog No. PIMA523079


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Description

Description

Peptide Sequence: VSHPRRSQER VSVHPHRLHP SFDFGQLQTP QPRYLAEGTD WDLSVDAGLS PAQFQVRPIP QHYQHYLATP RMHHFPRNSS STQMVVHEIR NYPYPQLHF

This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5 ft. UTR or in the 3 ft. coding region. These variants encode at least five different isoforms. [provided by RefSeq]
Specifications

Specifications

C18orf23
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
Human, Rat
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
3A1
Unconjugated
Liquid
C18orf23 (NP_689683, 122 a.a. ∽ 220 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Documents
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