MARCH4 Rabbit anti-Equine, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523146
DescriptionRNF174 (MARCH4) is a multi-pass membrane protein mainly found in the membrane of Golgi apparatus. It is a complex enzyme with a RING-CH-type zinc finger. It acts as a ubiquitin-protein ligase mainly involved in third step of ubiquitin conjugation. The RINGv-type zinc finger domain is required for E3 ligase activity in which the E3 ubiquitin-protein ligase mediates ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. It is mainly expressed in brain and placenta.
|Synthetic peptide (313 KVLNYDKTKDLEDQKAG 329) of RNF174/MARCH4 protein.|
|Antigen affinity chromatography|
|Equine, Human, Mouse, Non-human primate, Rat|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.2% gelatin and 0.05% sodium azide|
|MARCH-IV, RNF174, E3 ubiquitin-protein ligase MARCH4, RING finger protein 174, membrane-associated RING finger protein 4, membrane-associated RING-CH protein IV|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|100050538, 367295, 381270, 57574|
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