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MARCH4 Rabbit anti-Equine, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523146

Catalog No. PIPA523146


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Description

Description

RNF174 (MARCH4) is a multi-pass membrane protein mainly found in the membrane of Golgi apparatus. It is a complex enzyme with a RING-CH-type zinc finger. It acts as a ubiquitin-protein ligase mainly involved in third step of ubiquitin conjugation. The RINGv-type zinc finger domain is required for E3 ligase activity in which the E3 ubiquitin-protein ligase mediates ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. It is mainly expressed in brain and placenta.
Specifications

Specifications

MARCH4
Polyclonal
Unconjugated
MARCH4
Liquid
MARCH4
Synthetic peptide (313 KVLNYDKTKDLEDQKAG 329) of RNF174/MARCH4 protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Equine, Human, Mouse, Non-human primate, Rat
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.2% gelatin and 0.05% sodium azide
Q9P2E8, Q80TE3
MARCH-IV, RNF174, E3 ubiquitin-protein ligase MARCH4, RING finger protein 174, membrane-associated RING finger protein 4, membrane-associated RING-CH protein IV
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100050538, 367295, 381270, 57574
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