ROCK1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521130
A suggested positive control is 293 cell lysate. PA5-21130 can be used with blocking peptide PEP-1244.ROCK1 is a member of the AGC serine/threonine protein kinase family that regulates the assembly of the actin cytoskeleton. ROCK1 contains a protein kinase domain, a coiled-coil region and a zinc finger region and appears to be present as a dimer. ROCK1, like its isozyme ROCK2, is a downstream target of the small G-protein Rho and plays a role in smooth muscle contraction, maligt cell transformation, tumor invasion and metastasis, and mediates the cellular morphological changes during apoptosis.
|A 15 amino acid peptide near the amino terminus of human ROCK1.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 0.02% sodium azide|
|Q13464, P70335, Q63644|
|P160ROCK, ROCK-I; Rho kinase; p160 ROCK-1; p160-ROCK; renal carcinoma antigen NY-REN-35; rho-associated protein kinase 1; rho-associated, coiled-coil-containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase I|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|19877, 6093, 81762|
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