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ROCK1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521130

Catalog No. PIPA521130


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Description

Description

A suggested positive control is 293 cell lysate. PA5-21130 can be used with blocking peptide PEP-1244.

ROCK1 is a member of the AGC serine/threonine protein kinase family that regulates the assembly of the actin cytoskeleton. ROCK1 contains a protein kinase domain, a coiled-coil region and a zinc finger region and appears to be present as a dimer. ROCK1, like its isozyme ROCK2, is a downstream target of the small G-protein Rho and plays a role in smooth muscle contraction, maligt cell transformation, tumor invasion and metastasis, and mediates the cellular morphological changes during apoptosis.
Specifications

Specifications

ROCK1
Polyclonal
Unconjugated
ROCK1
Liquid
ROCK1
A 15 amino acid peptide near the amino terminus of human ROCK1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q13464, P70335, Q63644
P160ROCK, ROCK-I; Rho kinase; p160 ROCK-1; p160-ROCK; renal carcinoma antigen NY-REN-35; rho-associated protein kinase 1; rho-associated, coiled-coil-containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase I
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
19877, 6093, 81762
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