ROCK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521131
A suggested positive control is mouse brain tissue lysate. PA5-21131 can be used with blocking peptide PEP-1245.ROCK2 is a member of the AGC serine/threonine protein kinase family that regulates the assembly of the actin cytoskeleton. ROCK2 contains a protein kinase domain, a coiled-coil region and a zinc finger region and appears to be present as a dimer. ROCK2, like its isozyme ROCK1, is a downstream target of the small G-protein Rho and plays a role in smooth muscle contraction, maligt cell transformation, tumor invasion and metastasis, and mediates the cellular morphological changes during apoptosis.
|A 15 amino acid peptide near the center of human ROCK2.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|O75116, P70336, Q62868|
|ROCK-II; p164 ROCK-2; rho-associated protein kinase 2; rho-associated, coiled-coil-containing protein kinase II|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|19878, 25537, 9475|
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