RORA Rabbit anti-Bovine, Canine, Chicken, Equine, Human, Mouse, Non-human primate, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523268
DescriptionRORA is a receptor for retinoic acid belonging to the NR1 subfamily of nuclear hormone receptors with a nuclear receptor DNA binding domain. RORA binds either as a monomer or as a homodimer to the retinoic acid response element and thus regulates gene expression and also controls cell function. Though the exact function of RORA is yet unknown, it interacts with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, NM23-1, the product of a tumor metastasis suppressor candidate gene, CDK7, NCOA3 and NCOA6 coactivators. It is found to express in mesenchymal stem cells derived from bone marrow and are known to act by direct modulation of a bone matrix component. It is widely expressed in most of the tissues. Chromosomal aberrations involving RORA may be a cause of acute promyelocytic leukemia (APL).
|Synthetic peptide (94 SKKQRDSLYAEVQKHR 109) of ROR alpha protein.|
|Antigen affinity chromatography|
|Bovine, Canine, Chicken, Equine, Human, Mouse, Non-human primate|
|PBS with 0.05% BSA and 0.05% sodium azide; pH 8.0|
|NR1F1, ROR1, ROR2, ROR3, RZR-ALPHA, RZRA, ROR-alpha, nuclear receptor ROR-alpha, nuclear receptor RZR-alpha, nuclear receptor subfamily 1 group F member 1, retinoic acid receptor-related orphan receptor alpha, retinoid-related orphan receptor alpha, thyroid hormone nuclear receptor alpha variant 4, transcription factor RZR-alpha|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|100147460, 19883, 415377, 478328, 535597, 6095|
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