CD180 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520250
Despite its predicted molecular weight, RP105 often migrates at 95-105kDa in SDS-PAGE. A suggested positive control is human spleen tissue lysate. PA5-20250 can be used with blocking peptide PEP-0372.Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins. One such protein is RP105, a recently identified homolog to TLR4 that, with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. It has also been suggested that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.
|A 14 amino acid peptide from near the carboxy terminus of human RP105.|
|Antigen affinity chromatography|
|Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|LY64, Ly78, CD180 antigen, lymphocyte antigen 64, lymphocyte antigen-64 radioprotective, radioprotective 105 kDa protein|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
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