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CD180 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520252

Catalog No. PIPA520252


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Description

Description

Despite its predicted molecular weight, RP105 often migrates at 95-105kDa in SDS-PAGE. A suggested positive control is human spleen tissue lysate. PA5-20252 can be used with blocking peptide PEP-0374.

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins. One such protein is RP105, a recently identified homolog to TLR4 that, with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. It has also been suggested that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.
Specifications

Specifications

CD180
Polyclonal
Unconjugated
CD180
Liquid
CD180
A 14 amino acid peptide from near the center of human RP105.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q99467, Q62192
LY64, Ly78, CD180 antigen, lymphocyte antigen 64, lymphocyte antigen-64 radioprotective, radioprotective 105 kDa protein
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
17079, 4064
Documents
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