RPA2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA123299
PA1-23299 detects RPA32 in Human and Mouse samples. PA1-23299 has been successfully used in Western Blot procedures. PA1-23299 immunogen corresponds to Full-length human RPA-32 expressed in E. coli. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Replication protein A (RPA) is a single-stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 70, 32 and 14 kDa. This protein complex is highly conserved in eukaryotes and is essential in DNA replication, homologous recombination and nucleotide excision repair. RPA has been shown to be a target for DNA-dependent protein kinase (DNA-PK) ataxia telangiectasia-mutated gene (ATM) and a cyclin dependent protein kinase. The middle subunit, RPA-32, is phosphorylated during the S-phase of the cell cycle, in response to DNA damage and during apoptotsis of Jurkat T- lymphocytes.
|PBS with no preservative; pH 7.4|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|Full-length human RPA-32 expressed in E. coli.|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|