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POLR3H Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA524861

Catalog No. PIPA524861


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Description

Description

RPC8 is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. It is acting as nuclear and cytosolic DNA sensor involved in innate immune response. It can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.
Specifications

Specifications

POLR3H
Polyclonal
PBS with 0.09% sodium azide
Q9Y535, Q9D2C6
RPC22.9, RPC8, DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide, DNA-directed RNA polymerase III subunit H, DNA-directed RNA polymerase III subunit RPC8, RNA nucleotidyltransferase (DNA-directed), RNA polymerase III subunit 22.9 kDa subunit, RNA polymerase III su
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
171568, 78929
Flow Cytometry, Western Blot
Unconjugated
POLR3H
Liquid
POLR3H
KLH conjugated synthetic peptide between 5-33 amino acids from the N-terminal region of human RPC8
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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