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S6 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA526041

Catalog No. PIPA526041


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Description

Description

This antibody is predicted to react with bovine, chicken, non-human primate, rat and Xenopus based on sequence homology.

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Specifications

Specifications

S6
Polyclonal
PBS with 0.09% sodium azide
P62753, P62754
S6, 40S ribosomal protein S6, phosphoprotein NP33
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
20104, 6194
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
RPS6
Liquid
RPS6
KLH conjugated synthetic peptide between 220-249 amino acids from human RPS6
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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