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RUNX2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA514816

Catalog No. PIPA514816


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Description

Description

Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
Specifications

Specifications

RUNX2
Polyclonal
PBS with 0.09% sodium azide
Q13950
Runt-related transcription factor 2; Core-binding factor subunit alpha-1; CBF-alpha-1; Acute myeloid leukemia 3 protein; Oncogene AML-3; Polyomavirus enhancer-binding protein 2 alpha A subunit; PEBP2-alpha A; PEA2-alpha A; SL3-3 enhancer factor 1 alpha A subunit; SL3/AKV core-binding factor alpha A subunit; Osteoblast-specific transcription factor 2; OSF-2; RUNX2; AML3; CBFA1; OSF2; PEBP2A
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
860
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
RUNX2
Liquid
RUNX2
KLH conjugated synthetic peptide between 445-474 amino acids surrounding S465 of human RUNX2
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
Documents
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