RUVBL1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523452
DescriptionRvbs have been implicated in human pathologies, including carcinogenesis. For example Rvb1 overexpresssion has been reported in colon carcinoma, and Rvb1 SUMOylation has been shown to increase the proliferation and growth of prostate cancer cells. Rvb1 may also play a role in autoimmunity as high levels of RUVB1 autoantibodies have been detected in the sera of patients with autoimmune diseases including polymyositis/dermatomyosistic and autoimmune hepatitis. The extensive involvement of Rvbs in DNA-associated processes, including their interaction with a wide range of transcription factors, suggests that Rvb dysregulation may be involved in a number of other pathological processes yet to be elucidated.
|A portion of amino acids 400-454 of human Rvb1 was used as the immunogen.|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.05% BSA and 0.05% sodium azide|
|ECP54, INO80H, NMP238, PONTIN, Pontin52, RVB1, TIH1, TIP49, TIP49A, 49 kDa TATA box-binding protein-interacting protein, 49 kDa TBP-interacting protein, 54 kDa erythrocyte cytosolic protein, ECP-54, INO80 complex subunit H, NMP 238, RuvB (E coli homolog)-like 1, TAP54-alpha, TATA binding protein interacting protein 49 kDa, TIP60-associated protein 54-alpha, nuclear matrix protein 238, pontin 52, ruvB-like 1|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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