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S1P1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523471

Catalog No. PIPA523471


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Description

Description

S1P1 is a G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that is coupled to the G(i) subclass of heteromeric G proteins. S1P1 signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. It plays an important role in cell migration via its role in the reorganization of the actin cytoskeleton and formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. S1P1 is required for normal chemotaxis toward sphingosine 1-phosphate, normal embryonic heart development, and normal cardiac morphogenesis.
Specifications

Specifications

S1P1
Polyclonal
Unconjugated
S1PR1
Liquid
S1PR1
Synthetic peptide (32 TGKLNISADKENSIK 46) of S1PR1 protein.
Protein A
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
P21453
CD363, CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, S1P1, S1P receptor 1, S1P receptor Edg-1, endothelial differentiation G-protein coupled receptor 1, endothelial differentiation, sphingolipid G-protein-coupled receptor, 1, sphingosine 1-phosphate receptor 1, sphingosine 1-phosphate receptor EDG1, sphingosine 1-phosphate receptor Edg-1
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
1901
Documents
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