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p70 S6 Kinase, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527853

Catalog No. PIPA527853

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.

PA5-27853 targets S6K in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.The PA5-27853 immunogen is recombinant fragment corresponding to a region within amino acids 259 and 525 of Human S6K.
Specifications

Specifications

S6K
Polyclonal
Unconjugated
RPS6KB1
Purified
RPS6KB1
Recombinant fragment corresponding to a region within amino acids 259 and 525 of Human S6K
Antigen affinity chromatography
Store at -20°C, Avoid Freeze/Thaw Cycles
Primary
6198
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
P23443, Q8BSK8
PS6K, S6K, S6K1, STK14A, p70(S6K)-alpha, p70-S6K, p70-alpha, 70kDa ribosomal protein S6 kinase 1, P70S6K1, S6K-beta-1, p70 S6 kinase, alpha 1, p70 S6 kinase, alpha 2, p70 S6K-alpha, p70 S6KA, ribosomal protein S6 kinase I, ribosomal protein S6 kinase beta-1, serine/threonine kinase 14 alpha, serine/threonine-protein kinase
Rabbit
IgG
100μL
Antibody
Polyclonal
Human, Murine
Documents
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