p70 S6 Kinase, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527853
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.PA5-27853 targets S6K in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.The PA5-27853 immunogen is recombinant fragment corresponding to a region within amino acids 259 and 525 of Human S6K.
|Recombinant fragment corresponding to a region within amino acids 259 and 525 of Human S6K|
|Antigen affinity chromatography|
|Store at -20°C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|PS6K, S6K, S6K1, STK14A, p70(S6K)-alpha, p70-S6K, p70-alpha, 70kDa ribosomal protein S6 kinase 1, P70S6K1, S6K-beta-1, p70 S6 kinase, alpha 1, p70 S6 kinase, alpha 2, p70 S6K-alpha, p70 S6KA, ribosomal protein S6 kinase I, ribosomal protein S6 kinase beta-1, serine/threonine kinase 14 alpha, serine/threonine-protein kinase|
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