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hnRNP M1-M4 Mouse anti-Bovine, Human, Mouse, Porcine, Rabbit, Rat, Clone: 1D8, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA116673
Description
Suggested positive control: antigen standard for HNRNPM (transient overexpression lysate).
Proteins that directly bind to nascent RNA polymerase II transcripts, the heterogenous nuclear ribonucleoproteins (hnRNPs), play an important role in both transcript-specific packaging and alternative splicing of pre-mRNAs. A group of abundant hnRNPs, the M1-M4 proteins, appear as a cluster of four proteins. The M proteins are pre-mRNA binding proteins in vivo, and they bind avidly to poly (G) and poly (U) RNA homopolymers in vitro. M proteins are members of the ribonucleoprotein consensus sequence family of RNA-binding proteins with greatest similarity to a hypothetical RNA-binding protein from Saccharomyces cerevisiae. The M proteins also possess an unusual hexapeptide-repeat region rich in methionine and arginine residues (MR repeat motif) that resembles a repeat in the 64kDa subunit of cleavage stimulation factor, which is involved in 3 ft.-end maturation of pre-mRNAs. Proteins immunologically related to M exist in divergent eukaryotes ranging from human to yeast.Specifications
hnRNP M1-M4 | |
Monoclonal | |
Unconjugated | |
HNRNPM | |
Liquid | |
HNRNPM | |
M19 fusion protein containing full-length human protein. | |
200 μL | |
-20° C, Avoid Freeze/Thaw Cycles | |
Primary | |
100356502, 100514153, 116655, 4670, 515290, 76936 |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin) | |
1D8 | |
ascites with 0.1% sodium azide | |
P52272, Q9D0E1, Q62826 | |
heterogeneous nuclear ribonucleoprotein M, HNRNPM, HNRNPM4, HNRPM, hnRNA-binding protein M4, HNRNPM3, hnRNA-binding protein M3, HNRNP3, N-acetylglucosamine receptor 1, M4 protein | |
Mouse | |
IgG1, kappa | |
RUO | |
Antibody | |
Monoclonal | |
Bovine, Human, Mouse, Porcine, Rabbit, Rat |
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