hnRNP M1-M4 Mouse anti-Bovine, Human, Mouse, Porcine, Rabbit, Rat, Clone: 1D8, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA116673
Suggested positive control: antigen standard for HNRNPM (transient overexpression lysate).Proteins that directly bind to nascent RNA polymerase II transcripts, the heterogenous nuclear ribonucleoproteins (hnRNPs), play an important role in both transcript-specific packaging and alternative splicing of pre-mRNAs. A group of abundant hnRNPs, the M1-M4 proteins, appear as a cluster of four proteins. The M proteins are pre-mRNA binding proteins in vivo, and they bind avidly to poly (G) and poly (U) RNA homopolymers in vitro. M proteins are members of the ribonucleoprotein consensus sequence family of RNA-binding proteins with greatest similarity to a hypothetical RNA-binding protein from Saccharomyces cerevisiae. The M proteins also possess an unusual hexapeptide-repeat region rich in methionine and arginine residues (MR repeat motif) that resembles a repeat in the 64kDa subunit of cleavage stimulation factor, which is involved in 3′-end maturation of pre-mRNAs. Proteins immunologically related to M exist in divergent eukaryotes ranging from human to yeast.
|P52272, Q9D0E1, Q62826|
|M19 fusion protein containing full-length human protein.|
|100356502, 100514153, 116655, 4670, 515290, 76936|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)|
|heterogeneous nuclear ribonucleoprotein M, HNRNPM, HNRNPM4, HNRPM, hnRNA-binding protein M4, HNRNPM3, hnRNA-binding protein M3, HNRNP3, N-acetylglucosamine receptor 1, M4 protein|
|Bovine, Human, Mouse, Porcine, Rabbit, Rat|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok