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SAP30L Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA14371

Catalog No. PA14371


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Description

Description

PA1-4371 detects SAP30L from human samples. PA1-4371 has been successfully used in Western blot procedures. PA1-4371 immunizing peptide corresponds to amino residues 165-183 from human SAP30L Protein.

A novel TGF- beta up-regulated mRNA species, the Sin3-associated protein 30-like, SAP30L has been identified. The predicted nuclear localization signal of SAP30L is sufficient for nuclear transport of the protein although mutating it does not completely remove SAP30L from the nuclei. By reason of its nuclear localization and close homology to SAP30 it is thought that SAP30L might have a role in recruiting the Sin3-histone deacetylase complex to specific co-repressor complexes in response to TGF-beta, leading to the silencing of proliferation-driving genes in the differentiating intestinal epithelial cells.
Specifications

Specifications

SAP30L
Polyclonal
Unconjugated
SAP30L
Liquid
SAP30L
Synthetic Peptide: V(165) K S N K S R L D Q K S E G G K Q L E(183)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9HAJ7
DKFZp667L2214, FLJ11526, FLJ23595, FLJ36497, NS4ATP2
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
79685
Documents
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