SAP30L Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA14371
PA1-4371 detects SAP30L from human samples. PA1-4371 has been successfully used in Western blot procedures. PA1-4371 immunizing peptide corresponds to amino residues 165-183 from human SAP30L Protein.A novel TGF- beta up-regulated mRNA species, the Sin3-associated protein 30-like, SAP30L has been identified. The predicted nuclear localization signal of SAP30L is sufficient for nuclear transport of the protein although mutating it does not completely remove SAP30L from the nuclei. By reason of its nuclear localization and close homology to SAP30 it is thought that SAP30L might have a role in recruiting the Sin3-histone deacetylase complex to specific co-repressor complexes in response to TGF-beta, leading to the silencing of proliferation-driving genes in the differentiating intestinal epithelial cells.
|Synthetic Peptide: V(165) K S N K S R L D Q K S E G G K Q L E(183)|
|Antigen affinity chromatography|
|PBS with 0.02% sodium azide|
|DKFZp667L2214, FLJ11526, FLJ23595, FLJ36497, NS4ATP2|
|-20° C, Avoid Freeze/Thaw Cycles|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok