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SAPAP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520531

Catalog No. PIPA520531


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Description

Description

A suggested positive control is human brain tissue lysate. PA5-20531 can be used with blocking peptide PEP-0651.

SAP90/PSD-95-associated protein 1 (SAPAP1, also known as DLGAP1 or GKAP) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP1 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP1 mRNA is targeted to cell bodies in a similar manner to SAPAP2 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. SAPAP1 protein however, is targeted to the synapse and is not reliant on the synaptic localization of PSD-95 or the synaptic scaffolding molecule (S-SCAM).
Specifications

Specifications

SAPAP1
Polyclonal
Unconjugated
DLGAP1
Liquid
DLGAP1
An 18 amino acid peptide from near the center of human SAPAP1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
O14490, Q9D415, P97836
DAP-1, DAP-1-ALPHA, DAP-1-BETA, GKAP, SAPAP1, hGKAP; PSD-95/SAP90 binding protein 1; SAP90/PSD-95-associated protein 1; disks large-associated protein 1; guanylate kinase-associated protein
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
224997, 65040, 9229
Documents
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