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CXCL12 Mouse anti-Human, Clone: 79018, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523759
Reconstitute at 0.5 mg/mL in sterile PBS.CXCL12, Stromal cell derived factor beta 1 (SDF1) is a 70 amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. This member of the intercrine alpha (chemokine CxC) family is a chemoattractant active on T lymphocytes, monocytes, but not neutrophils. Targeted deletion of SDF1 gene resulted in defects of B cell lymphopoiesis and bone marrow myelopoiesis in mice. SDF1 has been shown to be chemotactic for lymphocytes. In addition, SDF1 was recently reported to be a ligand for CXCR4 (LESTR/fusin) and a co receptor for HIV1 entry into T cells (SDF1 binding to CXCR4 inhibits HIV1 entry).
|PBS with 5% trehalose and No Preservative|
|Stromal cell-derived factor 1, hSDF-1, C-X-C motif chemokine 12, Intercrine reduced in hepatomas, IRH, hIRH, Pre-B cell growth-stimulating factor, PBSF, CXCL12, SDF1, SDF1A, SDF1B|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)|
|E. coli-derived recombit human CXCL12/SDF-1 alpha Lys22-Lys89|
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