Influenza A H1N1 HA Rabbit anti-Virus, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520712
This antibody detects a peptide sequence that differs from Product No. PA5-20713 and PA5-20715, and can be used as a cognate pair with Product No. PA5-20731. PA5-20712 can be used with blocking peptide PEP-0827.Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States. The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic. Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible Neuraminidase (NA) surface proteins. The Hemagglutinin protein facilitates viral attachment while Neuraminidase is involved in viral release. These proteins also elicit immune responses that prevent infection or independently reduce viral replication. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. The distinct antigenic properties of the new swine influenza virus compared with seasonal influenza A (H1N1) virus suggest that human immunity against new swine influenza virus is limited, although the age distribution of reported cases suggests some degree of protection in older age groups.
|Influenza A H1N1 HA|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|PBS with 0.02% sodium azide|
|Influenza H1N1; H1N1 HA; H1N1 hemagglutinin|
|A synthetic peptide from the Hemagglutinin protein.|
|Antigen affinity chromatography|
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