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SEC61A1 Rabbit anti-Canine, Human, Mouse, Porcine, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA3014

Catalog No. PA3-014

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

The Sec61 complex is responsible for translocation of proteins across the rough endoplasmic reticulum membrane. Sec61 is composed of three subunits: alpha, beta, and gamma; that associate to form a heterotrimer. Multiple heterotrimers associate forming the ER translocon. Sec61 alpha is a polytopic protein that has ten membrane-spanning loops. Sec61 has been found to be tightly associated with membrane bound ribosomes, either directly or through adaptor proteins, and is required for assembly of membrane and secretory proteins.

PA3-014 detects human, canine and porcine, rat and mouse sec61 alpha from microsomes and shows no cross-reactivity with other sec61 isoforms.PA3-014 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~38kDa protein representing sec61 alpha from pig microsomes. The PA3-014 immunogen is a synthetic peptide corresponding to residues C(13) V I L P E I Q K P E R K I Q F K E K(31) of canine sec61 alpha. This sequence is completely conserved between human, mouse, rat, and canine.
Specifications

Specifications

SEC61A1
Polyclonal
whole serum with 0.05% sodium azide
P38377, P61619, P61620, P61621
Sec61 Complex Alpha Subunit
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
100155306, 29927, 404006, 53421, 80843
Western Blot
Unconjugated
SEC61A1
Liquid
SEC61A1
Synthetic peptide corresponding to residues C(13) V I L P E I Q K P E R K I Q F K E K(31) of canine SEC61 alpha.
NA
RUO
Antibody
Polyclonal
Canine, Human, Mouse, Porcine, Rat
Documents
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