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SEPP1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528281

Catalog No. PIPA528281


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Description

Description

PA5-28281 targets Selenoprotein P in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-28281 immunogen is recombit protein fragment corresponding to a region within amino acids 157 and 411 of Human Selenoprotein P. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3 ft. UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space. Several transcript variants, encoding either the same or different isoform, have been found for this gene.
Specifications

Specifications

SEPP1
Polyclonal
Unconjugated
SELENOP
Liquid
SELENOP
Recombit protein fragment corresponding to a region within amino acids 157 and 411 of Human Selenoprotein P
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
P49908
SELP, SeP, selenoprotein P
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
6414
Documents
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