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Septin 2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527485

Catalog No. PIPA527485


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Description

Description

PA5-27485 targets Septin 2 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-27485 immunogen is recombit fragment corresponding to a region within amino acids 1 and 175 of Human Septin 2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
Specifications

Specifications

Septin 2
Polyclonal
Unconjugated
SEPT2
Liquid
SEPT2
Recombit fragment corresponding to a region within amino acids 1 and 175 of Human Septin 2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 40% glycerol and 0.01% thimerosal; pH 7
Q15019
DIFF6, NEDD5, Pnutl3, hNedd5, NEDD-5, neural precursor cell expressed developmentally down-regulated protein 5, neural precursor cell expressed, developmentally down-regulated 5, septin-2
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
4735
Documents
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