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SQSTM1 Rabbit anti-Human, Invitrogen™

Rabbit Recombinant Polyclonal Antibody

Manufacturer:  Invitrogen 710539

Catalog No. PI710539


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Description

Description

Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain. Recombit rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombit monoclonal antibodies, providing the best of both worlds – the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombit antibody. While functionally the same as a polyclonal antibody – recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets – a recombit rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.

p62 is a scaffold protein which plays an important role in autophagy by acting a link in recognizing ubiquinated targets and presenting them to autophagic machinery. The N-terminus of p62 aids in polymerization, while the C-terminus aids in binding to ubiquinated proteins and to autophagosomal proteins like LC3. p62 is ubiquitously expressed in adult tissues. It co-localizes with ubiquinated proteins in protein bodies found in the cytosol and nucleus, or within autophagosomes and lysosomal structures.
Specifications

Specifications

SQSTM1
Recombinant Polyclonal
0.5 mg/mL
PBS with 0.09% sodium azide
Q13501
A170, OSIL, PDB3, ZIP3, p60, p62, p62B, EBI3-associated protein of 60 kDa, EBI3-associated protein p60, EBIAP
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
8878
Immunocytochemistry, Immunofluorescence, Western Blot
11HCLC
Unconjugated
SQSTM1
Liquid
SQSTM1
Peptide corresponding to amino acids 90–104 & 254–268 of human p62
Protein A
RUO
Antibody
Oligoclonal
Human
SDS
Documents
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